ABSTRACT
Several new pyrazole, pyrazolo [5, 1-c]-1, 2, 4-triazine, pyrimidine and thiazole derivatives were synthesised by the reactions of 2-bromo-1-benzofurylglyoxal-2-[3-phenyl-pyrazol-5-yl]-hydrazone with a variety of reagents. Structures were established by elemental and spectral data
Subject(s)
Triazines/chemistry , Pyrimidines/chemistry , /chemistryABSTRACT
Several new pyrrolidino [3,4-b] benzothiazolo [3',2'-a'] pyridinedione derivatives were synthesized via the dipolar cycloaddition reaction of several 2-benzothiazolylacrylonitriles with several N-arylmaleimides. The antischistosomal activity of a variety of these derivatives is tested. Structures are based on elemental and spectral data
Subject(s)
Pyrrolidines/chemical synthesis , Pyridines/pharmacology , Acrylonitrile/chemistry , Schistosomicides/chemical synthesis , Schistosomicides/chemistryABSTRACT
Several new pyrrolidino- and pyrrolo-[4, 3-b] furochromone derivatives were synthesized via the dipolar cycloaddition reactions of some styrylfurochromones with N-arylmaleimide and subsequent dehydrogenation. Structures are confirmed by elemental analysis and spectral data studies
Subject(s)
Pyrrolidines/chemical synthesis , Pyrroles/chemical synthesis , Pyrrolidines/analogs & derivatives , Pyrroles/analogs & derivativesABSTRACT
A variety of new pyrazole, pyrrolinopyrazole and pyrazolopyridazine derivatives were synthesised via the dipolar cycloaddition reactions of acrylonitrile, ethyl acrylate and N-arylmaleimides with the nitrile imine regenerated from 2-bromo-1- benzofurylglyoxal-2-[3-phenylpyrazol-5-yl]-hydrazone. Structure of the newly synthesized derivatives were established on the basis of elemental analysis and spectral data